NASDAQ · IONS

Ionis Pharmaceuticals, Inc.

$55.96 -$0.59 (-1.04%) 1D After hours

Key Metrics

$9.35B
Market cap
P/E · TTM
$1.06B
Revenue · TTM
−$326.98M
Net income
EPS · TTM $-2.06
Dividend yield
Free cash flow −$971.26M
Beta · 1Y 0.15
EBITDA · TTM −$314.01M
Gross margin

The Story So Far

LAST 6 MONTHS PRIMARY SOURCES ONLY
  • Jul 20
    From its Feb 6 high, the share price fell 39%.

    Peak close $86.50 on Feb 6; trough close $52.95 on Jul 20. The drawdown is the fact — the chapters around it are the context.

    RECEIPT: PRICE SERIES, PEAK-TO-TROUGH -39%
  • Jul 16
    Money rotated out of high-beta cohorts market-wide.

    High-beta names lagged the blue-chips by 20.3 points over ten sessions around this date. Stocks in that cohort weren't falling alone — they fell together.

    RECEIPT: ROTATION GAUGE, LIVE
  • Jul 10
    The stock moved -9.4% in a single session.

    Sessions this size usually pair with a chapter above or below — a filing, a headline, or the whole cohort moving together.

    RECEIPT: DAILY BAR, Jul 10
  • Jul 9
    The stock moved -23.9% in a single session.

    Sessions this size usually pair with a chapter above or below — a filing, a headline, or the whole cohort moving together.

    RECEIPT: DAILY BAR, Jul 9

The story updates itself as events post · The wolf reports; you decide

Snapshot

Market cap$9.35B
Enterprise value
Shares outstanding165.3M
52-wk range$40.03 – $86.74
Avg volume · 20D1.5M
Net cash
Book value / share$3.10
IndustryPharmaceutical Preparations
ExchangeNASDAQ
About Ionis Pharmaceuticals, Inc.
IPO dateMay 17, 1991
Employees1402

Ionis Pharmaceuticals is the leading developer of antisense technology to discover and develop novel drugs. Its broad clinical and preclinical pipeline targets a wide variety of diseases, with an emphasis on cardiovascular, metabolic, neurological, and rare diseases.

Wolf Grade COMING SOON

The wolf is in training. Composite grades vs sector — profitability, health, value, momentum — arrive with the percentile engine. Methodology will be public.

Valuation

P/E
P/S8.83
P/FCF
EV/EBITDA
EV/Sales
Graham №

Profitability

Gross
Operating -30.7%
Net -30.9%
FCF -91.8%
ROE / ROIC -60.6% · 22.9%

Financial Health

Current ratio4.10
Quick ratio4.09
Debt / equity
Debt / EBITDA
Net cash
Working capital$2.22B

Cash Flow · TTM

Operating CF −$910.63M
Capex −$60.63M
Free cash flow −$971.26M
Buybacks
Dividends paid
Shareholder yield

Piotroski F-Score

4 / 9
Middling fundamentals · 4 of 9 signals passing

Altman Z-Score

1.6
Distress zone (< 1.81) · elevated risk

Graham Number vs Price

Requires positive earnings and book value
Fundamentals through 2026-03-31 · computed by TickerWolf from SEC filings