NASDAQ · UPB

Upstream Bio, Inc.

$6.41 +$0.01 (+0.16%) 1D After hours

Key Metrics

$348.29M
Market cap
P/E · TTM
$3.32M
Revenue · TTM
−$156.76M
Net income
EPS · TTM $-2.92
Dividend yield
Free cash flow
Beta · 1Y 0.98
EBITDA · TTM −$171.77M
Gross margin

The Story So Far

LAST 6 MONTHS PRIMARY SOURCES ONLY
  • Jul 16
    Money rotated out of high-beta cohorts market-wide.

    High-beta names lagged the blue-chips by 18.6 points over ten sessions around this date. Stocks in that cohort weren't falling alone — they fell together.

    RECEIPT: ROTATION GAUGE, LIVE
  • Jun 16
    From its Jan 30 high, the share price fell 81%.

    Peak close $31.08 on Jan 30; trough close $5.92 on Jun 16. The drawdown is the fact — the chapters around it are the context.

    RECEIPT: PRICE SERIES, PEAK-TO-TROUGH -81%
  • Feb 13
    The stock moved -31.6% in a single session.

    Sessions this size usually pair with a chapter above or below — a filing, a headline, or the whole cohort moving together.

    RECEIPT: DAILY BAR, Feb 13
  • Feb 11
    The stock moved -47.2% in a single session.

    Sessions this size usually pair with a chapter above or below — a filing, a headline, or the whole cohort moving together.

    RECEIPT: DAILY BAR, Feb 11

The story updates itself as events post · The wolf reports; you decide

Snapshot

Market cap$348.29M
Enterprise value
Shares outstanding54.4M
52-wk range$5.85 – $33.68
Avg volume · 20D562.1K
Net cash
Book value / share$5.67
IndustryPharmaceutical Preparations
ExchangeNASDAQ
About Upstream Bio, Inc.
IPO dateOct 11, 2024
Employees75

Upstream Bio Inc is a clinical-stage biotechnology company developing treatments for inflammatory diseases, with an initial focus on severe respiratory disorders.

Wolf Grade COMING SOON

The wolf is in training. Composite grades vs sector — profitability, health, value, momentum — arrive with the percentile engine. Methodology will be public.

Valuation

P/E
P/S104.84
P/FCF
EV/EBITDA
EV/Sales
Graham №

Profitability

Gross
Operating -5,176.5%
Net -4,719.0%
FCF
ROE / ROIC -40.5% · —

Financial Health

Current ratio23.14
Quick ratio
Debt / equity
Debt / EBITDA
Net cash
Working capital$302.61M

Cash Flow · TTM

Operating CF −$139.96M
Capex
Free cash flow
Buybacks
Dividends paid
Shareholder yield

Piotroski F-Score

2 / 9
Weak fundamentals · 2 of 9 signals passing

Altman Z-Score

12.6
Safe zone (> 2.99) · bankruptcy risk negligible

Graham Number vs Price

Requires positive earnings and book value
Fundamentals through 2026-03-31 · computed by TickerWolf from SEC filings